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Anxiety Medication for Heart Palpitations: What Works, Why It Works, and When to Consider It


Heart palpitations—those rapid, pounding, or fluttering sensations in your chest—are among the most distressing symptoms people experience during anxiety. Even when you logically know it’s “just anxiety,” the physical intensity can convince your body that something is dangerously wrong. For many individuals, therapy and lifestyle changes help significantly—but when palpitations are persistent, severe, or disruptive, anxiety medication may be necessary to calm the body’s stress response.

At Favor Mental Health, we help patients understand what’s happening inside their bodies, determine whether medication is appropriate, and design treatment plans that address both the root and the symptoms of anxiety. This article explains the best medication options for anxiety-induced heart palpitations, how they work, and how to know when it’s time to consider them.


A woman sits on a sofa holding a pill and water, with tea, tablet, and photos on the table. Text: What Works, Why It Works, When to Consider It.
A woman sits on a sofa holding a pill and water, with tea, tablet, and photos on the table. Text: What Works, Why It Works, When to Consider It.


Understanding Heart Palpitations Caused by Anxiety

When anxiety hits, the brain activates the fight-or-flight response. This triggers a cascade of physiological reactions:

  • Release of adrenaline

  • Rapid activation of the sympathetic nervous system

  • Increased heart rate

  • Forceful or irregular heartbeat

  • Heightened awareness of bodily sensations

These biological shifts are normal, but they feel alarming. The fear of the palpitations then worsens anxiety, creating a loop:

Anxiety → palpitations → fear → more anxiety → more palpitations

Medication can help break this cycle by calming the nervous system and reducing the physiological response that fuels the panic.

When Medication for Heart Palpitations May Be Needed

Medication may be appropriate when:

  • Palpitations are frequent and interfere with daily functioning

  • You experience panic attacks with cardiac symptoms

  • Lifestyle and therapeutic strategies haven’t been enough

  • Palpitations trigger chronic fear or avoidance behaviors

  • You have co-occurring anxiety disorders (GAD, panic disorder, PTSD)

  • Sleep is affected by nighttime heart racing

  • Worry about your heart is worsening your anxiety

A mental health provider will conduct a full evaluation to determine whether the palpitations are purely anxiety-related or if a medical evaluation is needed first.

Types of Anxiety Medications That Help With Heart Palpitations

Medication choices depend on what’s triggering the palpitations, how often they occur, and the individual’s unique psychological and physical profile. Below are the most effective medication classes used clinically at Favor Mental Health.

1. SSRIs (Selective Serotonin Reuptake Inhibitors)

Best for: Chronic anxiety, panic disorder, generalized anxiety disorder, trauma-related anxiety.

SSRIs are one of the most effective long-term treatments for anxiety-related palpitations.

Common SSRIs:

  • Sertraline

  • Escitalopram

  • Fluoxetine

  • Paroxetine

  • Citalopram

How SSRIs help with palpitations

  • Reduce overall anxiety sensitivity

  • Lower the brain’s stress response

  • Decrease internal hypervigilance

  • Prevent panic episodes that trigger fast heartbeat

  • Improve sleep, reducing nighttime palpitations

SSRIs take several weeks to reach full effect but significantly reduce the frequency and intensity of palpitations over time.

2. SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors)

Best for: Anxiety with physical symptoms like muscle tension, body-based anxiety, or chronic palpitations.

Common SNRIs:

  • Venlafaxine

  • Duloxetine

Why SNRIs help

  • Improve mood and anxiety

  • Reduce the physical overstimulation that fuels palpitations

  • Help regulate the autonomic nervous system

SNRIs are especially effective when palpitations occur alongside chronic worry or somatic anxiety.

3. Beta Blockers

Best for: Situational or physical-anxiety states with strong bodily symptoms.

Unlike SSRIs and SNRIs—which treat anxiety itself—beta blockers treat the physical symptoms of anxiety.

Common beta blockers:

  • Propranolol

  • Atenolol

How beta blockers help with palpitations

  • Slow the heart rate

  • Reduce the force of cardiac contractions

  • Prevent adrenaline from binding to heart receptors

  • Reduce shaking, sweating, trembling

They are ideal for:

  • Performance anxiety

  • Social anxiety triggering heart racing

  • Isolated episodes of panic

  • Public speaking

  • High-stress events

Beta blockers work quickly and are taken as needed, but they do not treat the root anxiety.

4. Hydroxyzine (Antihistamine Anxiolytic)

Best for: Acute anxiety episodes, sleep disturbance, or panic-related palpitations.

Hydroxyzine works within 30 minutes and is non-addictive, making it a safe option for short-term relief.

Clinical benefits

  • Sedates overactive nerves

  • Lowers anxiety quickly

  • Helps with nighttime anxiety and palpitations

  • Useful when crying, panic, or adrenaline surges occur

Patients who experience nighttime heart racing often benefit from this medication.

5. Benzodiazepines (Short-Term, Highly Controlled Use)

Best for: Severe panic attacks with overwhelming cardiac symptoms—used only when strictly necessary.

Examples:

  • Lorazepam

  • Alprazolam

  • Clonazepam

How benzodiazepines help

  • Rapidly calm panic

  • Stop adrenaline surges

  • Reduce catastrophic thinking

  • Slow racing heart instantly

Because benzodiazepines carry dependency risks, they are used carefully and only for short-term clinical situations.

How Providers Choose the Right Medication

At Favor Mental Health, medication decisions are personalized, not one-size-fits-all. Providers consider:

  • Severity of palpitations

  • Frequency of panic attacks

  • Co-existing mental health conditions

  • Sleep quality

  • Stress levels

  • Medical history

  • Sensitivity to medication

  • Daily functioning and quality of life

The goal is to choose the safest, most effective, and most sustainable option.

Medication + Therapy = Best Results

Medication reduces the physiological symptoms.Therapy reduces the psychological triggers.

This combination targets both sides of the anxiety-palpitations cycle.

Effective therapeutic approaches include:

  • CBT to reframe catastrophic thoughts about the heart

  • Exposure therapy for panic

  • Stress and nervous system regulation

  • Trauma-informed therapy for individuals with past trauma

  • Mind–body techniques (breathing, grounding, somatic work)

Together, therapy and medication bring long-term stability.

Lifestyle Support to Enhance Medication Effectiveness

Medication works best when paired with heart- and anxiety-friendly habits:

  • Reduce caffeine and stimulants

  • Maintain hydration

  • Improve sleep consistency

  • Practice regular nervous-system calming techniques

  • Increase gentle movement (walks, yoga, stretching)

  • Avoid excessive alcohol or nicotine

  • Learn emotional regulation strategies

These practices lower baseline adrenaline and strengthen the body’s resilience.

When to Seek Immediate Medical Help

While anxiety is a common cause of palpitations, seek medical attention if palpitations are accompanied by:

  • Chest pain

  • Fainting

  • Shortness of breath

  • Irregular heartbeat

  • Severe dizziness

  • A history of heart conditions

Favor Mental Health frequently collaborates with primary care and cardiology to ensure total safety and peace of mind.

Favor Mental Health: Your Partner in Anxiety & Heart Palpitation Care

At Favor Mental Health, we understand how terrifying heart palpitations can be—even when they’re caused by anxiety. With over 17 years of experience, we offer:

✔ Comprehensive mental health evaluations

✔ Tailored anxiety treatment plans

✔ Medication management

✔ Therapy for panic, trauma, and chronic stress

✔ Support for sleep and lifestyle changes

✔ Substance abuse treatment

✔ Compassionate, confidential care

Location: Suite 9B, 260 Gateway Drive, Bel Air, MD 21014

Phone: 410-403-3299

You don’t have to endure anxiety-driven heart palpitations alone.With the right treatment plan, your mind and heart can work together in peace again.


 
 
 

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